Posted on April 29th 2010
Abstract Children surviving premature birth present with a wide spectrum of motor, sensory and cognitive disabilities, ranging from
slight motor deficits, school difficulties and behavioural problems to cerebral palsy and mental retardation. The anatomic
and functional substrate of these problems can be investigated using a variety of imaging techniques. Cranial US coupled with
colour Doppler is a well-established method for the initial diagnosis of intraventricular haemorrhage, parenchymal haemorrhagic
infarct and periventricular leukomalacia. MRI is useful for the follow-up study of brain maturation. Conventional T1- and
T2-weighted sequences, magnetization transfer and diffusion tensor imaging coupled with sophisticated tools of tissue segmentation
and analysis at a vox...
Posted on April 29th 2010
Abstract: Background: There is increasing demand for a standardised and reliable protocol for the objective assessment of upper limb motion in clinical populations. This paper describes the repeatability of a three-dimensional (3D) kinematic model and protocol to assess upper limb movement for children with and without cerebral palsy (CP).Methods: Ten typically developing (TD) children and seven children with CP (spastic hemiplegia) completed upper limb motion analysis on two occasions separated by at least one week. Participants performed three trials of four functional tasks, where 3D joint angles were calculated at the thorax, shoulder, elbow and wrist. Within and between-day repeatability was assessed using coefficients of multiple determination (CMD).Findings: There were distinct kine...
Posted on April 29th 2010
Abstract: Background: There is increasing demand for a standardised and reliable protocol for the objective assessment of upper limb motion in clinical populations. This paper describes the repeatability of a three-dimensional (3D) kinematic model and protocol to assess upper limb movement for children with and without cerebral palsy (CP).Methods: Ten typically developing (TD) children and seven children with CP (spastic hemiplegia) completed upper limb motion analysis on two occasions separated by at least one week. Participants performed three trials of four functional tasks, where 3D joint angles were calculated at the thorax, shoulder, elbow and wrist. Within and between-day repeatability was assessed using coefficients of multiple determination (CMD).Findings: There were distinct kine...
Posted on April 29th 2010
Conclusion: In our study, the number of congenital cytomegalovirus infections in children with cerebral cortical malformations was higher (4/26) than expected with reference to the birth prevalence (0.2[ndash]0.5%) of congenital cytomegalovirus infection in Sweden. We thus conclude that congenital cytomegalovirus infection should be considered in children with cortical malformations of unknown origin. (Source: Acta Paediatrica)
Posted on April 29th 2010
Aim To determine whether there is a difference between perspectives of functioning and health-related quality of life (HRQL) of parents and ambulatory adolescents with spastic cerebral palsy (CP).Method A total of 139 parent patient pairs (73 females, 66 males; median age 14y 6mo, age range 11[ndash]18y, Gross Motor Function Classification System [GMFCS] levels I[ndash]III, with hemiplegia [n=23], diplegia [n=103], triplegia [n=9], and quadriplegia [n=4]) were recruited from outpatient CP clinics at three pediatric orthopaedic hospitals, between 2000 and 2006, from whom Pediatric Outcomes Data Collection Instrument (PODCI) responses were collected.Results Cross-sectional data, calculated with intraclass correlation coefficients [ICC], showed parents and adolescents agreed more on functioni...
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