Posted on July 31st 2010
Conclusions: The MobQues47 is a unidimensional scale with excellent internal consistency that can be used to measure caregiver-reported mobility limitations in children with CP. (Source: Archives of Physical Medicine and Rehabilitation)
Posted on July 31st 2010
Abstract: The neonatal brain is very vulnerable to injury due to its relatively large size, rapid rate of development and immature immunological systems. Injury at this time often results in lifelong neuro-developmental sequelae such as cerebral palsy, learning difficulties and sensory deficits. In the term brain injury is most commonly due to hypoxiaâischaemia during labour, but hyperbilirubinaemia, trauma, thrombosis and infections remain important causes.In the preterm infant, because of immaturity, the pattern of injury is different with forms of white matter damage predominating. Germinal matrix haemorrhage, parenchymal infarction and forms of periventricular leucomalacia predominate. Preterm white matter damage often leads to altered or reduced development of cortical grey matter s...
Posted on July 31st 2010
Abstract: Hypoxic-ischaemic encephalopathy is directly associated with the development of cerebral palsy and cognitive disabilities later in life, therefore remaining an important problem in perinatal medicine. Postnatal neuroprotective strategies have been investigated elaborately, but up to now, only moderate hypothermia proved to be beneficial in reducing post hypoxic-ischaemic encephalopathy in a selected group of asphyxiated neonates. Since the vast amount of toxic free radicals is produced in the reperfusion and reoxygenation period upon and immediately (30â60 min) after birth, we postulate that antenatal (i.e. maternal) pharmacologic neuroprotection of the foetus, combined with postnatal hypothermia, might be a more optimal approach to prevent this free radical induced brain damag...
Posted on July 31st 2010
Authors: Hayek S, Gershon A, Wientroub S, Yizhar Z
Our aim was to evaluate the effect of adding inhibitory casting to the treatment of young children with cerebral palsy who received injections of botulinum neurotoxin A (BoNT-A) to gastrocnemius for equinus gait. Of the 20 patients in the series, 11 in group A had inhibitory casts applied on the day of the first set of BoNT-A injections and nine in group B did not have casting. Both groups received another BoNT-A injection four months later. The patients were followed for eight months and examined at five intervals. Both groups showed significant improvement in gait parameters and function (p < 0.0001) and selective motor control (p = 0.041, - 0.036) throughout the study. Group A had significantly better passive dorsiflexion of the ...
Posted on July 31st 2010
Abstract: Intrapartum fetal surveillance is mandatory in every labour. Continuous electronic fetal heart rate monitoring (CEFM) remains the main method used in high-risk clinical situations. Although the use of CEFM has been shown to reduce the incidence of neonatal seizures, it has not reduced the incidence of cerebral palsy or neonatal encephalopathy. CEFM is technically easy to introduce but interpretation is subjective. Inter-observer and intra-observer differences are well recognized in the interpretation of cardiotocograph (CTG) traces. Standardization of interpretation using guidelines and training of staff can improve reliability in interpretation. CEFM should be used as a screening test with the addition of fetal scalp blood sampling (FBS) to confirm fetal acidâbase balance. Rec...
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