Posted on September 30th 2011
In the 3 large, well-done randomized placebo-controlled trials, antenatal magnesium sulfate (MgSO4) reduced the risk of cerebral palsy among children who survived early preterm birth. Crowther and colleagues studied 1062 women. Moderate or severe cerebral palsy (inability to walk unaided) was significantly less frequent among children in the MgSO4 group, 3.4% vs 6.6%. In the National Institutes of Health Maternal-Fetal Medicine Units Network trial (the BEAM trial) 2241 women were enrolled. As in the trial of Crowther et al, MgSO4 significantly reduced the risk of moderate to severe cerebral palsy, 1.9% vs 3.5%. Among the offspring of women randomized (Source: American Journal of Obstetrics and Gynecology)
Posted on September 30th 2011
In the 3 large, well-done randomized placebo-controlled trials, antenatal magnesium sulfate (MgSO4) reduced the risk of cerebral palsy among children who survived early preterm birth. Crowther and colleagues studied 1062 women. Moderate or severe cerebral palsy (inability to walk unaided) was significantly less frequent among children in the MgSO4 group, 3.4% vs 6.6%. In the National Institutes of Health Maternal-Fetal Medicine Units Network trial (the BEAM trial) 2241 women were enrolled. As in the trial of Crowther et al, MgSO4 significantly reduced the risk of moderate to severe cerebral palsy, 1.9% vs 3.5%. Among the offspring of women randomized (Source: American Journal of Obstetrics and Gynecology)
Posted on September 30th 2011
THE ISSUE: Cerebral palsy is infrequent, but causes devastating neurologic consequences in preterm infants. Three recent randomized trials and several metaanalyses have evaluated the role of antenatal magnesium sulfate for neuroprotection in patients at risk for early preterm delivery. Despite the recommendations from the metaanalyses, there is uncertainty about whether to treat or who to treat, if any, with magnesium sulfate. (Source: American Journal of Obstetrics and Gynecology)
Posted on September 30th 2011
The Australian Federal Productivity Commission is proposing two new schemes to better support those with major disability. The main National Disability Insurance Scheme (NDIS) will provide longâterm care and support for the disabled. A smaller scheme, the National Injury Insurance Scheme (NIIS), will provide ânoâfault âsupport for those following an accident or âmedical injuryâ. It is proposed that cerebral palsy (CP) is part of the NIIS. While this brings quicker and more equitable benefits to CP families, the scheme labels CP as a âmedical accidentâ and infers preventability. Obstetricians will fund much of the system. Despite being labelled a ânoâfaultâ system, maternity staff can still be litigated for extensive âhead of damagesâ, eg loss of earning capacity. ...
Posted on September 30th 2011
THE ISSUE: Cerebral palsy is infrequent, but causes devastating neurologic consequences in preterm infants. Three recent randomized trials and several metaanalyses have evaluated the role of antenatal magnesium sulfate for neuroprotection in patients at risk for early preterm delivery. Despite the recommendations from the metaanalyses, there is uncertainty about whether to treat or who to treat, if any, with magnesium sulfate. (Source: American Journal of Obstetrics and Gynecology)
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