Commentary
In their article, Sutphin et al seek to examine the development of antibodies to a specific formulation of botulinum toxin type A (Botox, Allergan, Irvine, CA) with a seemingly simple and straightforward experiment. The question of antibody formation in response to BTA is obviously of greater import in the functional world of medicine as opposed to the aesthetic world. When treating cervical dystonia or cerebral palsy spasm, doses are much higher, intervals are frequently shorter, and the consequences of losing your best treatment option are much greater than when treating an aesthetic patient. However, loss of the toxin as a cosmetic treatment is obviously something we would rather avoid, however rare those cases might be. (Source: Aesthetic Surgery Journal)
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