Septo-optic dysplasia-plus and dyskinetic cerebral palsy in a child
Abstract Septo-optic dysplasia (SOD), also called De Morsierâs syndrome, is a highly heterogeneous condition comprising a spectrum
of central nervous system malformations that involves in various degrees the optic nerves, the hypothalamicâpituitary axis,
and other midline structures such as the septum pellucidum and the corpus callosum. In a discrete number of cases, schizencephaly,
agenesis of the corpus callosum or other cortical malformations are associated (SOD-plus). The authors present a 6-year-old
boy with dyskinetic cerebral palsy (athetoid-dystonic subtype) associated with SOD-plus. Cranial magnetic resonance imaging
(cMRI) revealed the total absence of septum pellucidum, optic nerve hypoplasia, hypoplasia of the corpus callosum and right
occipital cortical dy…
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